Journal of Liver Cancer

Chang Wook Park

2 Articles

A Case of Hepatocellular Carcinoma Exhibited over Partial Response after Hepatic Arterial Infusion Chemotherapy: Chang Wook Park, Young Lan Kown, Yong Jin Kim, Yoon Jung Kim, Hye Jin Seo, Kyung In Lee, Eun Soo Kim, Byung Kook Jang, Woo Jin Jeong, Kyung Sik Park, Kwang Bum Jo, Jae Seok Hwang, Young Hwan Kim, Jung Hyuk Kwon; Journal of the Korean Liver Cancer Study Group. 2010;10(1):40-43. Published online June 30, 2010

Abstract PDF: Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis. Especially potal vein invasion is a grave prognostic indicator in the setting of HCC. There is currently no effective method for treatment of HCC with portal vein invasion. A 61-year-old female patient was diagnosed a massive HCCs in both hepatic lobe with portal vein thrombosis, based on computed tomography (CT) and increased tumor marker, α-fetoprotein. She was treated with intrahepatic arterial CDDP (10 mg on 1~5 day), 5-FU (250mg on 1~5 day) and leukovorin (12mg on 1~5 day) infusion via percutaneously implantable port system (PIPS) every 3 weeks, totally seven times. The patient was still living 6 months after first hepatic arterial infusion chemotherapy (HAIC) and follow-up CT showed partial response with necrosis of HCCs. We report here a case of advanced HCC with portal vein thrombosis that was effectively treated with HAIC via PIPS.

A Case of Hepatocellular Carcinoma Presenting with Rib Metastasis: Kyung In Lee, Young Lan Kwon, Yoon Jung Kim, Hye Jin Seo, Yong Jin Kim, Chang Wook Park, Eun Soo Kim, Byoung Kuk Jang, Woo Jin Chung, Kyung Sik Park, Kwang Bum Cho, Jae Seok Hwang, Jung Hyeok Kwon; Journal of the Korean Liver Cancer Study Group. 2010;10(1):64-68. Published online June 30, 2010

Abstract PDF: Bone metastasis is not uncommon and shows poor survival in patients with hepatocellular carcinoma (HCC). We describe a case of HCC presenting with rib metastasis in a 54-year-old man. In spite of radiotherapy for rib metastasis, pain was sustained and size of lesions were increased. So we performd CT-guided percutaneous ethanol injection therapy (PEIT). Whenever new metastatic bone lesions were detected, we have done PEIT. However, abdominal CT scan at 25th month after diagnosis shows residual viable tumors in pelvic bone and multiple metastatic nodules in both lung. He is alive by taking conservative management for 27 months after diagnosis.